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hydroxyprogesterone

CAS 68-96-2
20

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A progestin steroid hormone with documented endocrine activity and potential developmental toxicity, not authorized for cosmetic use.

Hydroxyprogesterone is a natural/progestational steroid hormone with documented pharmacological activity. As a hormone, it falls outside the scope of cosmetic ingredients in the EU — hormones and hormone-like substances are specifically addressed in CosIng Annex II as prohibited. The substance has no safety assessment for topical cosmetic use and raising concerns about systemic hormonal disruption if absorbed through skin. It is not listed as an approved cosmetic ingredient.

Known concerns

  • Endocrine-disrupting progestational activity
  • Not listed in CosIng — no cosmetic authorization
  • Potential developmental toxicity from systemic absorption
  • Hormone classification — subject to pharmaceutical regulation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.