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HYDROXYPROPYL BIS-HYDROXYETHYLDIMONIUM CHLORIDE

CAS -
78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Hydroxypropyl Bis-hydroxyethyldimonium Chloride is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Hydroxypropyl Bis-Hydroxyethyldimonium Chloride is a bis-quaternary ammonium compound where two hydroxyethyl-substituted dimethylamino groups are linked through a hydroxypropyl spacer. The hydroxy substituents reduce the overall cationic charge density, improving mildness compared to conventional single-quat conditioning agents like cetrimonium chloride. This makes it better tolerated on skin while maintaining excellent hair substantivity and anti-static performance. It is used in rinse-off and leave-in hair care products. No specific EU restrictions apply beyond standard cosmetic safety requirements under Regulation 1223/2009.

Known concerns

  • Quaternary ammonium compound - mild sensitisation potential at high concentrations
  • Generally mild for a cationic surfactant
  • Well-established hair conditioning agent

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.