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ITRACONAZOLE

CAS 84625-61-6
28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Itraconazole is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Itraconazole is a triazole antifungal used systemically for fungal infections. While topical ketoconazole is permitted in some anti-dandruff products, itraconazole itself is not listed in EU cosmetic Annexes for any use. It carries hepatotoxic risks and significant drug interaction potential. Cosmetic-grade topical use is not supported by current EU regulatory frameworks, and its inclusion in ingredient lists requires careful origin verification.

Skin benefits

  • Antifungal properties theoretically applicable to dandruff shampoos

Known concerns

  • Systemic antifungal drug — not approved for cosmetics
  • Hepatotoxic potential with systemic exposure
  • Drug interaction profile raises contamination concerns

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.