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LIQUIRITIGENIN

CAS 578-86-9
82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Liquiritigenin is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Liquiritigenin is a flavanone isolated from Glycyrrhiza species (licorice root), exhibiting antioxidant, anti-inflammatory, and tyrosinase-inhibiting activity. It is permitted for use in cosmetic products in the EU under Regulation (EC) No 1223/2009 with no specific restriction listed. As a botanical-derived flavonoid, it has a favorable safety profile though rare sensitization is possible.

Skin benefits

  • Antioxidant protection against free radicals
  • Anti-inflammatory skin soothing
  • Tyrosinase inhibition for brightening
  • Supports collagen stability

Known concerns

  • Rare potential for skin sensitization
  • Limited clinical safety data at high concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.