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N-(2-Niro-4-aminophenyl)-allylamine (HC Red No 16) and its salts

CAS 160219-76-1
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

HC Red No 16 (N-(2-Nitro-4-aminophenyl)-allylamine) is a nitroamino compound used as a hair dye intermediate. Nitroamino aromatic compounds are known for their sensitization potential and may cause cross-reactivity with other hair dye intermediates. The nitro group on the aromatic ring can also contribute to phototoxic reactions under UV exposure. While not explicitly listed in EU Annex II or III, the sensitization profile requires careful safety evaluation before cosmetic use, and the substance may require professional restriction.

Known concerns

  • Known skin sensitization potential
  • Potential phototoxicity from nitro group
  • May cause cross-reactivity with other hair dyes

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.