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Hair dye intermediate

N,N-DIMETHYL-P-PHENYLENEDIAMINE

CAS 99-98-9
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An aromatic diamine historically used in oxidative hair colorants. It is a well-known skin sensitizer related to PPD, with mutagenicity concerns, and is restricted in cosmetics under EU rules.

Skin benefits

  • Historical use as oxidative hair dye intermediate
  • Provides deep color development in permanent dyes
  • Reacts with couplers to form chromophores

Known concerns

  • Aromatic amine with strong skin sensitization potential
  • Cross-reactivity with PPD allergy
  • Suspected genotoxicity and mutagenicity
  • Restricted or prohibited in EU cosmetics
  • Can trigger severe allergic contact dermatitis

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related hair dye intermediates

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.