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N-PHENYL-P-PHENYLENEDIAMINE HCL

CAS 2198-59-6 / 56426-15-4
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A hair-dye precursor similar to its sulfate counterpart, posing moderate risk of skin sensitization and respiratory irritation.

A p-phenylenediamine hydrochloride salt listed in EU Annex III/8 for restricted use in hair-dye formulations. Classified as a skin sensitizer (H317) and acute toxicant (H302/H312/H332) under GHS, with eye irritation potential (H319). Its HCl salt form offers marginally better solubility but comparable allergenic risk to the sulfate, requiring professional formulation controls.

Known concerns

  • Skin sensitizer (H317) – potential for allergic reaction
  • Acute oral/lethal dermal toxicity (H302/H312/H332)
  • Eye irritant (H319)
  • Respiratory irritant (H335)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.