Skip to content

Other

NICOTINALDEHYDE

CAS 500-22-1
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Pyridine-3-carbaldehyde, a reactive aldehyde used as a chemical intermediate. Carries acute toxicity and skin/eye irritation hazards; rarely seen in finished cosmetics, and not appropriate for leave-on use.

Function

ANTIMICROBIAL

Skin benefits

  • Niacin/niacinamide synthesis intermediate
  • Reactive carbonyl flavor/aroma chemistry

Known concerns

  • GHS H302/H315/H319 acute toxicity & irritation
  • Reactive aldehyde — sensitization risk
  • Not a typical leave-on cosmetic ingredient

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related others

35
1,3-Benzenediamine, 4-methyl-, hydrochloride (1:1)
Other
 35
1,5-Di-(beta-hydroxyethylamino)-2-nitro-4-chlorobenzene (see note 17)
Other
 35
2,2'-Methylenebis(6-bromo-4-chlorophenol)
Other
 35
2,4-DIAMINO-5-METHYLPHENETOLE HCL
Other
 35
2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL
Other
 35
2-Ethylhexyl 4-(dimethylamino)benzoate / Padimate O (USAN:BAN)
Other
 35
3-(p-Chlorophenoxy)-propane-1,2-diol
Other
 35
3-Hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide
Other

Check your shelf

Find NICOTINALDEHYDE in your products.

Scan any cosmetic product with LuxSense to see if it contains NICOTINALDEHYDE and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.