Skip to content

Other

NICOTINALDEHYDE

CAS 500-22-1 Updated
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Pyridine-3-carbaldehyde, a reactive aldehyde used as a chemical intermediate. Carries acute toxicity and skin/eye irritation hazards; rarely seen in finished cosmetics, and not appropriate for leave-on use.

Function

ANTIMICROBIAL

Skin benefits

  • Niacin/niacinamide synthesis intermediate
  • Reactive carbonyl flavor/aroma chemistry

Known concerns

  • GHS H302/H315/H319 acute toxicity & irritation
  • Reactive aldehyde — sensitization risk
  • Not a typical leave-on cosmetic ingredient

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

35
1,3-Benzenediamine, 4-methyl-, hydrochloride (1:1)
Other
 35
1,5-Di-(beta-hydroxyethylamino)-2-nitro-4-chlorobenzene (see note 17)
Other
 35
2,2'-Methylenebis(6-bromo-4-chlorophenol)
Other
 35
2,4-DIAMINO-5-METHYLPHENETOLE HCL
Other
 35
2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL
Other
 35
2-Ethylhexyl 4-(dimethylamino)benzoate / Padimate O (USAN:BAN)
Other
 35
3-(p-Chlorophenoxy)-propane-1,2-diol
Other
 35
3-Hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide
Other

Check your shelf

Find NICOTINALDEHYDE in your products.

Scan any cosmetic product with LuxSense to see if it contains NICOTINALDEHYDE and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.