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Alkylphenol ethoxylate surfactant

NONOXYNOL-35

CAS 68412-54-4/ 9016-45-9 (generic)/ 26027-38-3 (generic)/ 37205-87-1 (generic)
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Nonoxynol-35 is an alkylphenol ethoxylate surfactant. It is a recognised endocrine disruptor with significant aquatic toxicity, and its use in personal care is heavily restricted in the EU under REACH.

Skin benefits

  • Effective non-ionic surfactant and emulsifier
  • Solubilises lipophilic actives in water-based formulas

Known concerns

  • Alkylphenol ethoxylate flagged as an endocrine disruptor and environmental hazard
  • Causes skin and eye irritation (H315/H319)
  • Toxic to aquatic life with long-lasting effects (H410/H411)
  • Restricted or phased out in many jurisdictions including the EU REACH framework
  • Manufacturing impurities can include 1,4-dioxane

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related alkylphenol ethoxylate surfactants

38
NONOXYNOL-44
Alkylphenol ethoxylate surfactant
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NONOXYNOL-30
Alkylphenol ethoxylate surfactant
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OCTOXYNOL-20
Alkylphenol ethoxylate surfactant
 55
NONYL NONOXYNOL-100
Alkylphenol ethoxylate surfactant

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.