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NONYL NONOXYNOL-10 PHOSPHATE

CAS 39464-64-7
59

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Nonyl Nonoxynol-10 Phosphate is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

NONYL NONOXYNOL-10 PHOSPHATE is the phosphate ester of nonoxynol-10 with 10 ethoxylate units. The relatively low EO count (10) compared to other nonoxynol phosphate variants means higher potential for nonyl phenol metabolite penetration. EU REACH has flagged nonyl phenyl ethoxylates for endocrine-disruption assessment. This substance is not specifically listed in EU cosmetics Annexes II or III, but falls within the 'known sensitizers, preservatives of concern' band due to metabolite toxicity and environmental concerns.

Skin benefits

  • emulsifying
  • surfactant

Known concerns

  • endocrine disruption potential (nonyl phenol metabolite)
  • environmental toxicity
  • skin sensitization potential (nonyl phenol)
  • ethylene oxide contamination (potential)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.