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NONYL NONOXYNOL-5

CAS 9014-93-1
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Nonyl Nonoxynol-5 is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Nonyl Nonoxynol-5 is a nonionic surfactant of the alkylphenol ethoxylate (APE) family, derived from nonylphenol condensed with approximately 5 moles of ethylene oxide. Nonylphenol and its short-chain ethoxylates (including Nonoxynol-5) are recognized as endocrine-disrupting chemicals (EDCs) in aquatic environments and are suspected of exhibiting estrogenic activity. The EU has progressively restricted nonylphenol ethoxylates in consumer products; they are classified as Article 14 substances under Regulation (EC) 1907/2006 (REACH) for restrictions on the marketing and use of certain dangerous substances. The CIR has deferred review of this ingredient class pending further regulatory evaluation.

Skin benefits

  • Effective surfactant and emulsifier with good solvency
  • Historical use in cosmetic cleansing formulations

Known concerns

  • Nonylphenol component is a suspected endocrine disruptor
  • Aquatic toxicity: persistent and harmful to aquatic organisms
  • Nonylphenol residues may be present as manufacturing by-products
  • Subject to EU REACH restrictions for dangerous substances

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.