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PEG-16

CAS 25322-68-3
79

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A low-to-medium molecular weight polyethylene glycol used as a humectant and solvent that helps dissolve other ingredients and keeps products from drying out on the skin.

PEG-16 is a polyethylene glycol polymer with approximately 16 ethylene oxide units. While lower than many other PEGs in this batch, 16 EO units still confer sufficient hydrophilicity for the ingredient to function as a water-soluble humectant and solvent. EU Cosmetics Regulation lists PEG-16 as a permitted cosmetic ingredient in Annex V (preservatives excluded). Standard purity requirements for residual monomers apply; residual ethylene oxide must be kept as low as technologically feasible, and 1,4-dioxane must be below detection thresholds relevant for cosmetics.

Skin benefits

  • Humectant that draws moisture to skin surface
  • Water-soluble solvent helping dissolve active ingredients uniformly

Known concerns

  • Lower EO degree relative to other PEGs increases potential for mild skin drying in some individuals
  • Residual monomer contamination must be stringently controlled
  • Use in broken skin should be considered in safety assessment

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.