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Bioactive peptide

PENTAPEPTIDE-59

75

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A five-amino-acid peptide used in anti-aging skincare to signal skin renewal pathways. Generally skin-friendly, though independent evidence of efficacy and long-term safety is limited.

Function

SKIN CONDITIONING

Skin benefits

  • Short peptide marketed for anti-aging signalling
  • Generally low irritation at cosmetic use levels
  • Water-soluble and easy to formulate
  • Stable under typical leave-on conditions

Known concerns

  • Supplier-driven efficacy data with little independent validation
  • No SCCS or CIR opinion specific to this peptide
  • Long-term effects not well documented
  • Often a premium-priced ingredient with modest measurable benefit

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related bioactive peptides

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.