Bioactive peptide
TETRAPEPTIDE-33
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A four-amino-acid peptide used in anti-aging serums to signal skin support. Generally well tolerated, though independent efficacy and long-term evidence remain limited.
Function
Skin benefits
- Short peptide marketed for skin-soothing and anti-aging effects
- Low irritation typical for cosmetic peptides
- Water-soluble and easy to incorporate
- Active at low use levels
Known concerns
- Mostly supplier-funded efficacy studies
- No independent SCCS or CIR opinion
- Limited long-term safety data
- Premium pricing relative to demonstrated benefit
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related bioactive peptides
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.