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Phytonadione [INCI], phytomenadione [INN]

CAS 84-80-0 -- 81818-54-4
88

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Phytonadione [inci], Phytomenadione [inn] is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Phytonadione (phytomenadione, Vitamin K1) is a fat-soluble vitamin that plays a role in blood coagulation factor synthesis. In cosmetics, it is used for its anti-inflammatory and skin-soothing properties, particularly in products targeting bruising, dark circles under the eyes, and post-procedure skin recovery. It is listed in EU Cosmetics Regulation Annexes and has an established safe use history in topical formulations at appropriate concentrations.

Skin benefits

  • Anti-inflammatory skin soothing
  • Bruise-fading properties
  • Supports skin healing and recovery
  • Antioxidant protection

Known concerns

  • Very rare potential for allergenicity
  • COSING presence indicates ongoing regulatory review

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.