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Banned Substance

Propoxyphene hydrochloride [USAN]

CAS 1639-60-7 Updated
2

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An opioid analgesic withdrawn from most markets after fatal cardiac arrhythmias. Listed in EU Annex II — banned in cosmetics. It is a controlled drug, not a topical ingredient.

Skin benefits

  • No legitimate benefit in cosmetics — banned

Known concerns

  • EU Annex II banned controlled opioid
  • Withdrawn from many markets due to cardiotoxicity
  • Abuse and overdose potential
  • Inappropriate for any cosmetic application

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.