Skip to content

Peptide

RH-POLYPEPTIDE-6

CAS 453656-85-4
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A recombinant human-identical polypeptide marketed for anti-aging and skin renewal. Promising mechanism but limited public safety data, and quality depends on tight control of manufacturing residuals.

Function

SKIN CONDITIONING

Skin benefits

  • Recombinant human-identical polypeptide intended to support skin renewal
  • May signal collagen and fibroblast activity in vitro
  • Used in high-end anti-aging formulations
  • Vegan-compatible when produced by microbial expression

Known concerns

  • Recombinant peptides have limited public safety and efficacy data
  • Possible immune sensitisation with repeated exposure to bioactive proteins
  • Manufacturing residuals (host cell proteins, endotoxin) must be controlled
  • No SCCS opinion on this specific peptide

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related peptides

Check your shelf

Find RH-POLYPEPTIDE-6 in your products.

Scan any cosmetic product with LuxSense to see if it contains RH-POLYPEPTIDE-6 and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.