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Fragrance

SCLAREOLIDE

CAS 564-20-5
80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Sclareolide — an amber-woody lactone from clary sage, also a key Ambroxan precursor. Widely used in fine fragrance with no GHS hazard classification at typical levels.

Skin benefits

  • Provides warm amber-woody odour
  • Effective at low dose
  • Stable in formulation

Known concerns

  • Fragrance allergen rules apply
  • IFRA category limits
  • Mild sensitisation possible above thresholds

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.