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SH-PENTAPEPTIDE-17 SP

82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic peptide that mimics a fragment of the human enzyme pappalysin-1, used in cosmetics for skin conditioning and improving the appearance of firmness.

SH-Pentapeptide-17 SP is a single-chain human peptide produced synthetically to be identical to a portion of Pappalysin-1, consisting of asparagine, aspartic acid, lysine, and methionine residues. It is not classified under EU Annex II or III restrictions and is considered a low-risk cosmetic ingredient, though as a relatively recent bioactive peptide, long-term post-market data remain limited. Peptides of this type are widely used in anti-aging formulations without significant safety signals in the literature.

Function

NOT REPORTED

Skin benefits

  • May support skin firmness and elasticity through matrix protein stimulation
  • Functions as a skin conditioning agent in cosmetic formulations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.