Skip to content

Other

TOLUENE-2,5-DIAMINE SULFATE

CAS 615-50-9
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An oxidative hair dye precursor used to produce dark shades, restricted in the EU to professional use only with strict concentration limits.

TOLUENE-2,5-DIAMINE SULFATE (also known as p-toluenediamine sulfate, PTDS) is an oxidative hair dye intermediate classified under EU Cosmetics Regulation 1223/2009 Annex III, part 9a, restricting its use in non-oxidative hair dye preparations and requiring specific concentration limits in oxidative products. It is a known severe skin sensitizer and is required to carry a cautionary statement regarding potential allergic reactions. The SCCS has assessed it as safe at restricted concentrations (≤10% after mixing) but flags it as a strong sensitizer.

Known concerns

  • Severe skin sensitizer – may cause allergic contact dermatitis
  • EU Annex III restricted (III/9a) – professional use only in oxidative formulations
  • Must be declared as a potential allergen

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

45
1-Methylamino-2- nitro-5-(2,3-dihydroxy-propyloxy)- benzene
Other
 45
2,3-DIMETHYL-4-FORMYL-1-PHENYL-5-PYRAZOLONE
Other
 45
2-(4-Amino-3-nitroanilino)ethanol
Other
 45
2-CYANOMETHOXY-P-PHENYLENEDIAMINE
Other
 45
2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE
Other
 45
2-METHYL-1-NAPHTHOL
Other
 45
2-[(4-Methoxy-2-nitrophenyl)azo]-3-oxo-N-(o-tolyl)butyramide
Other
 45
4-METHYL-2-PHENYL-2-PENTENAL
Other

Check your shelf

Find TOLUENE-2,5-DIAMINE SULFATE in your products.

Scan any cosmetic product with LuxSense to see if it contains TOLUENE-2,5-DIAMINE SULFATE and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.