Other
trengestone
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Trengestone is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.
Trengestone (16-methylene-17-alpha-hydroxy-19-nor-4-pregnene-3,20-dione) is a synthetic steroidal hormone related to progestins with potential pharmaceutical applications. Steroidal hormones and their derivatives are explicitly excluded from cosmetic use under EU Regulation (EC) No 1223/2009, as they fall under pharmaceutical legislation (Directive 2001/83/EC). The compound carries concerns related to hormonal activity and potential reproductive/developmental effects. Its presence in cosmetic ingredient databases is a misclassification, as hormonal substances require drug status and medical supervision. The SCCS has specifically addressed that hormonal substances have no place in cosmetic formulations regardless of concentration.
Known concerns
- Synthetic steroidal hormone
- Prohibited in EU cosmetics
- Pharmaceutical/medicinal classification
- Reproductive/developmental toxicity concerns
- Hormonal activity requiring medical supervision
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.