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4-ETHYL-ALPHA,ALPHA-DIMETHYL-BENZENEPROPANENITRILE

CAS 134123-93-6
57

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

4-ethyl-alpha,alpha-dimethyl-benzenepropanenitrile is a cosmetic ingredient used in product formulations. Note: classified as harmful to aquatic environments. Exercise caution due to limited available safety data.

4-Ethyl-alpha,alpha-dimethyl-benzenepropanenitrile is a nitrile-containing fragrance chemical with a branched C-4 ethyl substituent on a dimethyl phenylpropane backbone. Its H411 classification (toxic to aquatic life with long-lasting effects) requires consideration in formulation for aquatic toxicity risk. The nitrile group (-CN) is metabolically stable and does not readily convert to cyanide; however, the phenyl ring may undergo oxidative metabolism generating minor allergenic metabolites. EU REACH registration notes low biodegradability and the need for wastewater treatment consideration in product disposal.

Known concerns

  • Toxic to aquatic life with long lasting effects (H411)
  • Low biodegradability - persistence in wastewater
  • Nitrile group - structural alert for irritation in respiratory sensitization

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.