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4-NITROPHENYL AMINOETHYLUREA

CAS 27080-42-8
42

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A nitroaniline derivative hair dye intermediate with skin sensitisation and environmental toxicity concerns, listed in EU Annex III.

4-Nitrophenyl Aminoethylurea (note: original input listed as 'AMINOETHYLUREA' variant) is regulated under EU Annex III/249 of Cosmetics Regulation 1223/2009, restricting its use in hair dye products. Hazard statements H317 (skin sensitisation) and H412 (aquatic toxicity) indicate significant concerns. The nitro group and urea moiety contribute to its reactive nature, which underlies both its dyeing capability and its sensitising potential. Concentration limits under the Annex apply to finished products.

Known concerns

  • EU Annex III/249 restricted — concentration limits apply
  • Skin sensitisation H317
  • Aquatic toxicity H412

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.