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Antimicrobial

CAMELLIA SINENSIS SH-OLIGOPEPTIDE-1

80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A plant-produced recombinant human EGF analogue expressed in transgenic Camellia sinensis (tea plant), delivering growth-factor bioactivity with natural production platform benefits.

This recombinant protein replicates the 53-amino-acid sequence of human Epidermal Growth Factor and is produced in Camellia sinensis via transient expression or stable transgenesis. Plant expression systems offer advantages over bacterial systems including eukaryotic protein folding, reduced endotoxin risk, and absence of mammalian pathogens. Under EU Regulation 1223/2009, plant-produced recombinant proteins are treated similarly to microbial expressions — no specific restrictions apply. The ingredient's EGF bioactivity is the primary driver of its cosmetic functions.

Function

ANTIMICROBIALANTIOXIDANTHAIR CONDITIONING

Skin benefits

  • Antimicrobial through wound healing promotion
  • Antioxidant activity
  • Hair conditioning

Known concerns

  • EGF is a potent mitogen requiring concentration control
  • Plant expression may introduce secondary plant metabolites
  • Green tea allergens (if residual plant material present) could be a concern

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related antimicrobials

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.