Antimicrobial
ROSA DAMASCENA SH-OLIGOPEPTIDE-1
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A rose-plant-produced recombinant human EGF analogue offering growth-factor bioactivity with a natural botanical production platform that avoids bacterial endotoxin concerns.
This recombinant human EGF (53 amino acids) is expressed in Rosa damascena (damask rose) using transgenic technology. Plant production platforms, particularly in non-food botanicals, offer eukaryotic protein processing without bacterial endotoxin issues. The ingredient carries all functional attributes of human EGF, including keratinocyte mitogenic activity. EU cosmetics regulation (Regulation (EC) No 1223/2009) applies general safety provisions; no specific restrictions exist for plant-produced recombinant peptides of this type.
Function
Skin benefits
- Antimicrobial activity via growth factor wound response
- Antioxidant benefits
- Humectant skin conditioning
Known concerns
- EGF mitogenic potency requires appropriate use concentration
- Rose plant material may contain residual floral allergens
- Limited regulatory precedent for transgenic rose expression in cosmetics
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related antimicrobials
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.