Skin Conditioning
DECAPEPTIDE-72
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic 10-amino-acid peptide marketed as a skin-signaling conditioner. Used at very low levels; safety profile is plausible but independent data is thin.
Decapeptide-72 is a synthetic decapeptide (10 amino acids) supplied for cosmetic use as a skin-conditioning agent, typically targeting visible-aging endpoints. Like most numbered INCI peptides, it is sold by individual cosmetic ingredient houses and used at trace levels (often 1-100 ppm of peptide actives in finished formulas). It does not have a CIR or SCCS opinion, and there are no GHS hazard classifications published for it. Short peptides of this length generally show low irritation and low systemic exposure due to negligible skin penetration of intact molecules; the main uncertainties are formulation-specific (carriers, preservatives, trifluoroacetate counterions) and the lack of independent efficacy literature. Default risk profile is benign-to-neutral.
Function
Skin benefits
- Skin conditioning
- Marketed for visible-aging support
- Low irritation potential at use levels
Known concerns
- Sparse independent safety data
- No regulatory monograph
- Efficacy claims often supplier-only
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.