Skin Conditioning
TRIPEPTIDE-65
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic three-amino-acid peptide used as a skin-conditioning active. Low-risk by peptide class; specific evidence is thin.
Tripeptide-65 is a defined-sequence synthetic peptide of three amino acids used in skin-conditioning formulations. Tripeptides are very small; they typically penetrate poorly past the upper stratum corneum and are rapidly broken down by skin enzymes into individual amino acids. The class shows low irritation and sensitization. There is no specific CIR or SCCS review for Tripeptide-65, and independent efficacy data is sparse — most claims come from supplier in vitro work. Treated as low-risk, low-evidence.
Function
Skin benefits
- Skin conditioning
- Low irritation profile
- Rapid biodegradation
Known concerns
- Sparse independent data
- No formal regulatory dossier
- Supplier-driven claims
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.