Synthetic signal peptide
TRIPEPTIDE-65
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A short synthetic peptide used in skincare to convey anti-aging messaging around firmness and collagen support. Generally well tolerated, with efficacy claims largely supported by supplier-funded studies.
Function
Skin benefits
- Synthetic tripeptide intended to support collagen and elastin signaling
- Lightweight, water-soluble actives typically well tolerated
- Used in anti-aging formulations targeting firmness
- Low molecular weight allows surface skin penetration
Known concerns
- Marketing claims often exceed published clinical data
- Manufacturer studies dominate the evidence base
- Rare sensitization in sensitive individuals
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related synthetic signal peptides
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.