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Synthetic signal peptide

TRIPEPTIDE-107 BIS-CYCLOHEXYLPROPYL HISTIDINAMIDE

68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A lipophilically modified synthetic tripeptide marketed for anti-aging effects with enhanced skin penetration. Tolerance is generally good, but independent safety and efficacy data are scarce.

Skin benefits

  • Synthetic tripeptide derivative with anti-aging marketing positioning
  • Lipophilic groups may enhance skin penetration
  • Histidine moiety contributes antioxidant potential
  • Used at low concentrations in advanced formulations

Known concerns

  • Very limited independent safety and efficacy data
  • Bulky lipophilic groups can change skin tolerance versus simpler peptides
  • Manufacturer-led evidence base only
  • No CIR or SCCS specific review available

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.