Fragrance
HEXAHYDRO-TETRAMETHYLMETHANONAPHTHALEN-8-ONE
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A woody-amber fragrance ketone in the Iso E Super family — a workhorse of modern perfumery with a solid fragrance-industry safety record.
Hexahydro-tetramethylmethanonaphthalen-8-one (CAS 29461-13-0) is a saturated polycyclic ketone in the woody-amber Iso E Super family. It is one of the most widely used fragrance ingredients in modern fine fragrance and functional perfumery, valued for its smooth woody-amber character, diffusiveness, and substantivity. RIFM has extensive safety documentation for the class; rare cases of contact sensitization have been reported, primarily in perfume-handling occupational settings, but at normal leave-on cosmetic use levels the material has a strong safety record. Not an EU Annex III declared allergen. Good tier placement reflects widespread use with well-characterized profile.
Function
Skin benefits
- Woody-amber fragrance note
- Diffusivity and substantivity
- Iconic fine fragrance material
Known concerns
- Rare occupational contact sensitization
- Normal fragrance allergen load
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related fragrances
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.