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ISOSTEARAMIDOPROPYL EPOXYPROPYL DIMONIUM CHLORIDE

CAS 94349-35-6
42

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Isostearamidopropyl Epoxypropyl Dimonium Chloride is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Isostearamidopropyl epoxypropyl dimonium chloride is a dual-function quaternary ammonium compound with an epoxypropyl reactive group. The epoxy (glycidyl) moiety is a recognized skin sensitizer and can react with skin proteins to form complete allergens. This class of compounds is listed in EU Annex III of Regulation EC 1223/2009 with concentration restrictions. The combination of epoxy and quaternary ammonium functionalities makes it a higher-concern ingredient for skin sensitization.

Skin benefits

  • Provides strong conditioning and antistatic benefits from quaternary ammonium
  • Epoxypropyl group may enhance substantivity to hair protein

Known concerns

  • Epoxy group is a known skin sensitizer — reacts with skin proteins
  • EU Annex III restricted — concentration limits apply
  • Quaternary ammonium group adds surfactant-related irritation potential
  • Requires careful safety evaluation before use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.