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Skin Conditioning

NONAPEPTIDE-40

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic nine-amino-acid peptide used in skin-conditioning formulas. Low-risk by class; specific data is thin.

Nonapeptide-40 is a defined-sequence synthetic nine-amino-acid peptide used as a skin-conditioning agent. Nonapeptides are slightly larger than the more common tetra/penta/hexapeptides but still well within the low-skin-permeation range and still subject to rapid enzymatic breakdown into amino acids. The class shows favorable safety. No specific CIR or SCCS opinion exists. Independent efficacy data is essentially absent; claims rely on supplier in vitro work. Considered low-risk, low-evidence.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning
  • Low irritation
  • Defined synthetic sequence

Known concerns

  • Limited independent data
  • No regulatory review
  • Supplier-driven claims

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.