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TETRAPEPTIDE-63 ACETATE

85

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic tetrapeptide designed to target skin elasticity and firmness through fibroblast stimulation, used in advanced anti-aging skincare formulations.

Tetrapeptide-63 is a synthetic peptide of the GHK family (glycyl-histidyl-lysyl as core motif) with modification to improve enzymatic stability. It is listed in EU CosIng without restrictions, indicating broad approval for cosmetic use. Like other GHK-Cu mimetics, it modulates gene expression related to extracellular matrix repair. Available literature supports its use in anti-aging formulations with a safety profile consistent with other cosmetic peptides.

Skin benefits

  • Improves skin elasticity
  • Supports extracellular matrix repair
  • Anti-wrinkle efficacy
  • fibroblast stimulation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.