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Peptide active

DECA (SH-POLYPEPTIDE-180)

62

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A proprietary bioengineered signal peptide (SH-polypeptide-180) used in cosmetic serums for claimed skin-conditioning and anti-ageing effects on fine lines. Independent published safety data is limited.

Skin benefits

  • Bioengineered peptide marketed for anti-ageing signalling
  • Likely supports collagen and elastin pathways
  • Water soluble and easy to incorporate into serums

Known concerns

  • Proprietary sequence with little independent safety data
  • Penetration and stability poorly characterised
  • Potential for endotoxin if not manufactured to skincare grade

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.