Other
ETHYL CARBAZIDO HYALURONATE ACETYL HEXAPEPTIDE-8
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A cosmetic bioconjugate combining hyaluronic acid with the well-known anti-wrinkle peptide Acetyl Hexapeptide-8, designed for enhanced skin deposition and long-lasting effect.
Ethyl Carbazido Hyaluronate Acetyl Hexapeptide-8 is a hyaluronic acid-peptide conjugate listed on EU CosIng without specific restriction entries. Acetyl Hexapeptide-8 (Argireline) is a widely used cosmetic peptide recognised for its wrinkle-relaxing effect. The ethyl carbazido linker attaches the HA polymer to the peptide, potentially improving skin retention. No EU Annex restrictions apply; it is evaluated under the general safety provisions of Regulation 1223/2009.
Skin benefits
- Wrinkle-relaxing effect from Acetyl Hexapeptide-8
- Deep hydration from hyaluronic acid component
- Improved skin substantivity compared to free peptide
Known concerns
- Minor concerns about carbazido linker metabolism in skin
- Generally well tolerated; rare sensitisation reports for hexapeptide-8
- Quality depends on manufacturing purity
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.