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PHYTOSPHINGOSINE PCA

87

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Phytosphingosine Pca is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Phytosphingosine PCA is the salt of phytosphingosine with pyrrolidone carboxylic acid, functioning as a skin-identical lipid and natural moisturizing factor component. It is approved for cosmetic use with no EU restrictions and is recognized for its barrier-strengthening and antimicrobial activity against Cutibacterium acnes. The ingredient has a favourable safety profile supported by available toxicological data and is widely used in sensitive-skin and acne formulations.

Skin benefits

  • Reinforces the skin barrier by supporting ceramide synthesis
  • Exhibits broad-spectrum antimicrobial activity
  • Helps calm inflammation and reduce skin redness
  • Maintains skin hydration as part of the natural moisturizing factor

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.