Conditioning Agent
SH-POLYPEPTIDE-14
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A recombinant human nerve growth factor beta protein (241 amino acids) produced in E. coli for hair conditioning and skin protection.
A single-chain synthetic human Nerve Growth Factor Beta protein synthesized from the human gene, produced in E. coli. Contains up to 241 amino acids with possible disulfide bonds and/or glycosylation. NGF-beta is a neurotrophic factor involved in neuronal survival; topical cosmetic application follows standard safety monitoring under EU regulation EC 1223/2009.
Function
Skin benefits
- Hair conditioning properties
- Skin protection support
Known concerns
- Biological activity affecting nerve tissue
- Limited long-term human safety data for topical cosmetic use
- Potential for sensitization with repeated exposure
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related conditioning agents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.