Conditioning Agent
SH-POLYPEPTIDE-7 SH-OLIGOPEPTIDE-1
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A fusion recombinant peptide of 244 amino acids combining two human-derived sequences, produced in E. coli for skin protection.
A single-chain synthetic fusion peptide created by fusing sh-Polypeptide-7 and sh-Oligopeptide-1 genes, produced in E. coli. The 244-amino-acid chain may contain disulfide bonds and/or glycosylation. Both components are human-derived recombinant proteins with established cosmetic use profiles. EU regulation EC 1223/2009 applies standard safety requirements without specific restrictions.
Function
Skin benefits
- Skin protection and barrier support
Known concerns
- Large fusion protein size increases immunogenicity risk
- Limited long-term human safety data for topical cosmetic use
- Potential for sensitization with repeated exposure
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related conditioning agents
Check your shelf
Find SH-POLYPEPTIDE-7 SH-OLIGOPEPTIDE-1 in your products.
Scan any cosmetic product with LuxSense to see if it contains SH-POLYPEPTIDE-7 SH-OLIGOPEPTIDE-1 and get a full ingredient breakdown with safety scores.
This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.