Conditioning Agent
SH-POLYPEPTIDE-92
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetically produced human-identical peptide that supports skin conditioning by mimicking a growth factor found naturally in the body.
SH-Polypeptide-92 is a single-chain recombinant human peptide modeled on Growth Differentiation Factor 11, produced via E. coli fermentation. It consists of up to 407 standard amino acids and may include disulfide bonds and glycosylation. The EU cosmetics regulation does not restrict this ingredient; peptides of this type have a strong safety record in topical formulations with no reported sensitization.
Function
Skin benefits
- Supports skin conditioning and regeneration
- May promote collagen production
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related conditioning agents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.