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Chlorphenoxamine (INN)

CAS 77-38-3
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Chlorphenoxamine (INN) is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Chlorphenoxamine (CAS 77-38-3) is an antihistamine with anticholinergic properties, used as a pharmaceutical for treating allergic reactions and motion sickness. It has pharmacological activity entirely unrelated to cosmetic function—skin conditioning or cleansing. EU cosmetic regulation prohibits substances with systemic pharmacological activity that could interact with medications or cause adverse reactions. No cosmetic safety assessment has been conducted for this substance, and its inclusion in cosmetic databases is inappropriate.

Known concerns

  • Pharmaceutical antihistamine compound
  • Anticholinergic activity
  • No cosmetic safety assessment exists

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.