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Nalorphine

CAS 62-67-9
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Nalorphine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Nalorphine (N-allyl-normorphine) is an opioid antagonist and partial agonist at mu-opioid receptors, historically used as an antidote for opioid overdose. It is a derivative of morphine with substantial pharmacological activity affecting the central nervous system. No cosmetic usage is documented, and the compound lacks safety data for topical application. EU cosmetic regulations do not include this substance in any positive list.

Known concerns

  • Opioid receptor activity
  • CNS effects
  • No cosmetic safety data
  • Pharmacological compound not suitable for cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.