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NONOXYNOL-10

CAS 68412-54-4/ 9016-45-9 (generic)/ 26027-38-3 (generic)/ 37205-87-1 (generic)/ 27942-26-3/ 27177-08-8
24

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

This surfactant family is restricted in EU cosmetics due to endocrine disruption concerns linked to its nonylphenyl backbone, which breaks down into harmful nonylphenol.

Nonoxynol-10 is a nonionic surfactant belonging to the nonylphenyl ether class of ethoxylated compounds. It is restricted in cosmetic products within the EU under REACH Annex XVII due to its classification as an endocrine-disrupting substance; the alkylphenol moiety can degrade to nonylphenol (NP), a well-documented endocrine disruptor. Environmental risk is also significant, as NP and its ethoxylates are toxic to aquatic organisms and persist in the environment.

Known concerns

  • Endocrine disruption potential (nonylphenyl degradation)
  • EU REACH Annex XVII restriction in cosmetic products
  • Aquatic toxicity and environmental persistence
  • Potential reproductive toxicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.