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Antioxidant

SR-(METHIONYL S-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-58 HEXAPEPTIDE-40)

77

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A 205-amino-acid E. coli fusion peptide combining rainbow trout sequence with human-mimicking polypeptide domains, delivering antioxidant, emollient, and conditioning effects.

This fusion peptide is notable for its additional SKIN CONDITIONING — EMOLLIENT function designation, suggesting the sh-Polypeptide-58 domain contributes lipid-like or barrier-supporting properties beyond standard peptide bioactivity. Produced in E. coli, the ingredient falls outside EU restriction annexes. The 205-residue chain size (~23 kDa) indicates limited but potentially non-zero dermal bioavailability based on SCCS molecular-weight considerations for peptide ingredients.

Function

ANTIOXIDANTSKIN CONDITIONING - EMOLLIENTHAIR CONDITIONINGSKIN PROTECTINGSKIN CONDITIONING - HUMECTANT

Skin benefits

  • Antioxidant, skin protecting, humectant, and emollient conditioning
  • Hair conditioning

Known concerns

  • Endotoxin management required from E. coli host
  • Fish allergenicity for seafood-sensitised individuals
  • Emollient claim may require additional film-forming or lipid-component validation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.