Antioxidant
SR-(METHIONYL S-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-66 HEXAPEPTIDE-40)
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A 576-residue E. coli fusion peptide combining rainbow trout and human-mimicking domains, offering broad-spectrum antioxidant, protecting, and conditioning activities.
This fusion peptide is among the larger recombinant peptides in the series at 576 amino acids, combining rainbow trout s-Oligopeptide-1, sh-Polypeptide-66, and Hexapeptide-40. sh-Polypeptide-66 in CosIng is commonly associated with fibroblast growth factor (FGF) mimetics. The molecular size (~67 kDa) limits skin penetration significantly. EU regulatory status is unlisted in restriction annexes; the ingredient requires compliance with general product safety provisions. Endotoxin levels must be controlled to cosmetic-grade standards.
Function
Skin benefits
- Antioxidant, skin protecting, humectant, and miscellaneous conditioning
- Hair conditioning
Known concerns
- Large molecular size limits bioavailability to upper skin layers
- Endotoxin control required from E. coli host
- Fish allergenicity for sensitised consumers
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.