Antioxidant
SR-(METHIONYL S-RAINBOW TROUT OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-2 HEXAPEPTIDE-40)
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
An E. coli-produced fusion peptide incorporating rainbow trout oligopeptide with human-mimicking sequences, designed for antioxidant and multi-functional skin/hair conditioning.
This recombinant fusion peptide is assembled from three domains — rainbow trout s-Oligopeptide-1, human-mimicking sh-Oligopeptide-2, and Hexapeptide-40 — with an N-terminal methionine linker. Fish-derived peptides in cosmetics are a growing category, though allergenicity screening for aquagenic sensitivities is advisable. The production organism E. coli K-12 derived strains are generally regarded as non-pathogenic; however, standard cosmetic-grade manufacturing requires validated removal of residual DNA, endotoxin, and host proteins per ISO 11910 and SCCS guidance.
Function
Skin benefits
- Antioxidant activity
- Skin protecting and humectant properties
- Hair conditioning
Known concerns
- Fish-derived component may trigger seafood allergy
- E. coli fermentation requires endotoxin quality control
- Limited human clinical data for this specific combination
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.