Antioxidant
SR-(METHIONYL S-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-136 HEXAPEPTIDE-40)
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A 196-amino-acid E. coli fusion peptide with rainbow trout and human-mimicking domains, supporting antioxidant, protecting, and conditioning functions across skin and hair.
This fusion peptide combines s-Rainbow Trout Oligopeptide-1, sh-Polypeptide-136, and Hexapeptide-40 in a 196-residue chain produced in E. coli. The intermediate size (~22 kDa) suggests limited but not absent dermal penetration. sh-Polypeptide-136 sequences in CosIng have limited published data; safety assessment relies primarily on the component-domain approach. The ingredient is not listed in EU restriction Annexes I–VIII and must comply with general product safety requirements under Regulation (EC) No 1223/2009.
Function
Skin benefits
- Antioxidant activity
- Skin protecting, humectant, and miscellaneous conditioning
Known concerns
- E. coli endotoxin management essential
- Fish-derived domain allergenicity concern
- Novel sequence combination without extensive clinical data
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.