Antioxidant
SR-(METHIONYL S-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-13 HEXAPEPTIDE-40)
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A 226-amino-acid E. coli-derived fusion peptide combining rainbow trout oligopeptide with human-mimicking polypeptide sequences for broad skin and hair care applications.
This fusion peptide incorporates rainbow trout s-Oligopeptide-1, sh-Polypeptide-13, and Hexapeptide-40 domains linked via a methionine initiator. The 226-residue chain length reduces probability of significant dermal penetration, consistent with SCCS guidance on peptide molecular weight. sh-Polypeptide-13 sequences in CosIng typically correspond to vascular endothelial growth factor (VEGF) mimetics or related angiogenic peptides. Production follows standard recombinant E. coli fermentation with multi-step purification.
Function
Skin benefits
- Antioxidant activity
- Skin protecting and humectant conditioning
- Hair conditioning
Known concerns
- Endotoxin contamination concern from E. coli host
- Fish protein allergenicity for sensitised consumers
- VEGF-mimetic domain may warrant angiogenesis sensitivity review
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.