Antioxidant
SR-(METHIONYL S-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-69 HEXAPEPTIDE-40)
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
The largest in the rainbow trout fusion series at 429 amino acids, combining three peptide domains in an E. coli expression system for antioxidant and conditioning applications.
At 429 amino acids, this fusion peptide represents the upper size range for this ingredient family. The combination of rainbow trout s-Oligopeptide-1, sh-Polypeptide-69, and Hexapeptide-40 provides multiple bioactive domains. The large molecular weight (>50 kDa) means negligible dermal penetration based on biophysical principles. EU regulatory status is unlisted in restriction annexes; the ingredient falls under standard cosmetic safety requirements. The production host E. coli requires standard endotoxin controls per pharmaceutical-grade recombinant protein standards.
Function
Skin benefits
- Antioxidant activity
- Skin protecting and humectant conditioning
- Hair conditioning
Known concerns
- Very large size reduces skin penetration significantly
- Endotoxin and host-cell protein impurity management required
- Fish allergenicity for susceptible individuals
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.