Antioxidant
SR-(METHIONYL S-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-150 HEXAPEPTIDE-40)
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A 355-amino-acid E. coli-derived fusion peptide with rainbow trout and human-mimicking domains, serving antioxidant, protecting, and conditioning functions.
This fusion peptide combines s-Rainbow Trout Oligopeptide-1, sh-Polypeptide-150, and Hexapeptide-40 in a 355-residue chain. The intermediate-large size (~40 kDa) is consistent with reduced dermal penetration expectations. The ingredient is produced by standard E. coli fermentation and falls under general cosmetic safety provisions with no EU-specific restrictions noted. sh-Polypeptide-150 is a newer CosIng designation without extensive published safety literature.
Function
Skin benefits
- Antioxidant, skin protecting, and humectant conditioning
- Hair conditioning
Known concerns
- Larger size reduces skin penetration
- Endotoxin and host-cell protein removal essential
- Fish-derived sequence allergenicity concern
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.