Antioxidant
SR-(METHIONYL S-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-92 HEXAPEPTIDE-40)
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A triple-domain fusion peptide combining rainbow trout-derived oligopeptide with human-mimicking polypeptide sequences, produced in E. coli and displaying combined antioxidant and skin/hair conditioning activities.
This fusion peptide is expressed in E. coli via synthetic gene assembly, combining an N-terminal methionine-linked rainbow trout oligopeptide (likely derived from fish-tissue bioactivity) with sh-Polypeptide-92 and Hexapeptide-40 domains. The E. coli expression system is widely used for recombinant cosmetic peptides; however, endotoxin removal and host-cell protein purification are critical quality attributes. The ingredient is not listed in EU cosmetic regulation annexes and falls within the category of peptide-based ingredients that have emerged rapidly with advances in synthetic biology.
Function
Skin benefits
- Antioxidant protection
- Skin protecting and conditioning
- Hair conditioning
Known concerns
- Endotoxin contamination risk from E. coli host
- Fish-derived sequences may raise allergenicity concerns for seafood-allergic consumers
- Novel fusion sequence lacks long-term human safety data
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.