peptide
SR-(METHIONYL HEXAPEPTIDE-40 DECAPEPTIDE-66 METHIONYL SPIDER POLYPEPTIDE-3 OLIGOPEPTIDE-235)
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A recombinant fusion peptide combining spider-silk-analog polypeptide-3 with decapeptide-66 and hexapeptide-40 for skin signaling and structural claims. Cosmetic safety review and clinical data are limited.
Function
Skin benefits
- Combines pigmentation-targeting decapeptide-66 and structural spider-silk-analog motifs
- Recombinant production avoids harvesting spider silk directly from arthropods
Known concerns
- Spider-derived polypeptide-3 motifs are novel in cosmetics with minimal regulator review
- No SCCS or CIR opinion located for this construct
- Allergen relevance for arthropod-sensitive users unknown
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.